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Ensaios clínicos em recrutamento



Ensaios clínicos na área do carcinoma mama
  • OLYMPIA: A randomised, double-blind, parallel group, placebo-controlled multi-centre Phase III study to assess the efficacy and safety of olaparib versus placebo as adjuvant treatment in patients with germline BRCA1/2 mutations and high risk HER2 negative primary breast cancer who have completed definitive local treatment and neoadjuvant or adjuvant chemotherapy. 
Mais informações em: 
https://www.clinicaltrialsregister.eu/ctr-search/trial/2013-003839-30/PT

  • SOLAR-1: A phase III randomized double-blind, placebo controlled study of alpelisib in combination with fulvestrant for men and postmenopausal women with hormone receptor positive, HER2-negative advanced breast cancer which progressed on or after aromatase inhibitor treatment

Ensaios clínicos na área do carcinoma da pulmão:
    • GO29438: A phase III, open-label, randomized studyof atezolizumab (mpdl3280a, anti−pd-l1 antibody) in combination with carboplatin or cisplatin+pemetrexe compared with carboplatin or cisplatin+pemetrexed in patients who are chemotherapy-naive and have stage iv non-squamous non−small cell lung cancer.


    Ensaios clínicos na área da colite ulcerosa
    • EVOLUTION: An open label, single group assignment design study to correlate soluble ST2 with clinical, endoscopic and histological activity in moderate to severe Ulcerative Colitis patients under golimumab.
    Mais informações em:
    https://www.clinicaltrialsregister.eu/ctr-search/trial/2014-003262-25/PT

    • GARDENIA: Phase III, Randomized, Multicenter Double Blind, Double Dummy Study to evaluate the efficacy and safety of Etrolizumab compared with infliximab in patients with moderate to severe active ulcerative colitis who are naive to TNF inhibitors. 
    Mais informações em: 
    https://www.clinicaltrialsregister.eu/ctr-search/trial/2013-004282-14/PT

     
    Ensaios clínicos na área da diabetes:

      • FIDELIO: A randomized, double-blind, placebo-controlled, parallel-group, multicenter, event-driven Phase III study to investigate the efficacy and safety of finerenone, in addition to standard of care, on the progression of kidney disease in subjects with type 2 diabetes mellitus and the clinical diagnosis of diabetic kidney disease.

      • FIGARO: A randomized, double-blind, placebo-controlled, parallel-group, multicenter, event-driven Phase III study to investigate the efficacy and safety of finerenone on the reduction of cardiovascular morbidity and mortality in subjects with type 2 diabetes mellitus and the clinical diagnosis of diabetic kidney disease in addition to standard of care. 


      Ensaios clínicos na área da doença de Alzheimer:
      • BN29552: A phase III, multicenter, randomized, double- blind, placebo-controlled, parallel-group, efficacy and safety study of crenezumab in patients with prodomal-to-mild Alzheimer’s disease 
      Mais informações em: 
      https://www.clinicaltrialsregister.eu/ctr-search/trial/2015-003034-27/PL

      • 221AD301: A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects with Early Alzheimer's Disease
           Mais informações em: 

      • BI 12897: A multi-centre, double-blind, parallel-group, randomised controlled study to investigate efficacy, safety and tolerability of orally administered BI 409306 during a 12-week treatment period compared to donepezil and placebo in patients with cognitive impairment due to Alzheimer's Disease
           Mais informações em: 

      Ensaios clínicos na área do AVC:
      • RESPECT ESUS: Randomized, double-blind, Evaluation in secondary Stroke Prevention comparing the Efficacy and safety of the oral Thrombin inhibitor dabigatran etexilate (110 mg or 150 mg, oral b.i.d.) versus acetylsalicylic acid (100 mg oral q.d.) in patients with Embolic Stroke of Undetermined Source
      Mais informações em: 
      https://www.clinicaltrialsregister.eu/ctr-search/trial/2013-003444-24/PT

      Ensaios clínicos na área da esclerose múltipla:
      Ensaios clínicos na área do HIV-2
      • DTG-01-01: A Phase II, Multicenter, Single-Arm, Open-Label Clinical Trial to Evaluate the Safety and Efficacy of Triple Therapy with Dolutegravir plus 2 NRTIs, in Treatment-Naïve HIV-2 Infected Subjects


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      Luz Saúde, S.A., Sociedade Aberta © 2017